Physostigmine Salicylate

DRUG DESCRIPTION

Physostigmine Salicylate (physostigmine salicylate injection) Injection is a derivative of the Calabar bean, and
its active moiety, physostigmine, is also known as eserine. Its chemical structure
is:

C₁₅H₂₁N₃O₂•C₇H₆O₃
MW = 413.47

It is soluble in water and a 0.5% aqueous solution has a pH of 5.8.

Physostigmine Salicylate (physostigmine salicylate injection) Injection is available in 2 mL ampules, each mL containing
1 mg of Physostigmine Salicylate (physostigmine salicylate injection) in a vehicle composed of sodium metabisulfite
0.1%, benzyl alcohol 2.0% as a preservative in Water for Injection.