Romazicon

DRUG DESCRIPTION

ROMAZICON® (flumazenil) is a benzodiazepine receptor antagonist. Chemically,
flumazenil is ethyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a](1,4)
benzodiazepine-3-carboxylate. Flumazenil has an imidazobenzodiazepine structure,
a calculated molecular weight of 303.3, and the following structural formula:

Flumazenil is a white to off-white crystalline compound with an octanol:buffer partition coefficient of 14 to 1 at pH 7.4. It is insoluble in water but slightly soluble in acidic aqueous solutions. ROMAZICON (flumazenil) is available as a sterile parenteral dosage form for intravenous administration. Each mL contains 0.1 mg of flumazenil compounded with 1.8 mg of methylparaben, 0.2 mg of propylparaben, 0.9% sodium chloride, 0.01% edetate disodium, and 0.01% acetic acid; the pH is adjusted to approximately 4 with hydrochloric acid and/or, if necessary, sodium hydroxide.

What are the possible side effects of flumazenil (Romazicon)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• seizures (convulsions);


• weak or shallow breathing;


• continued drowsiness for longer than 2 hours after receiving flumazenil;


• confusion, fear, panic attack; or


• fast or uneven heart rate.

Less serious side effects include:

...

Read All Potential Side Effects and See Pictures of Romazicon »

Romazicon Patient Information Including Side Effects

Brand Names: Romazicon

Generic Name: flumazenil (Pronunciation: floo MAZ e nil)

• What is flumazenil (Romazicon)?


• What are the possible side effects of flumazenil (Romazicon)?


• What is the most important information I should know about flumazenil (Romazicon)?


• What should I discuss with my health care provider before receiving flumazenil (Romazicon)?


• How is flumazenil given (Romazicon)?


• What happens if I miss a dose (Romazicon)?


• What happens if I overdose (Romazicon)?


• What should I avoid while receiving flumazenil (Romazicon)?


• What other drugs will affect flumazenil (Romazicon)?


• Where can I get more information?

What is flumazenil (Romazicon)?

Flumazenil reverses the effects of certain types of sedatives from the benzodiazepine (ben-zo-dye-AYZ-e-peen) group of drugs. This includes Valium, Xanax, Tranxene, Librium, ProSom, Dalmane, Ativan, Restoril, Halcion, and others.

Flumazenil is used to reverse the sedative effects of a benzodiazepine when used during surgery or other medical procedure. Flumazenil is also used to treat benzodiazepine overdose.

Flumazenil may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of flumazenil (Romazicon)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• seizures (convulsions);


• weak or shallow breathing;


• continued drowsiness for longer than 2 hours after receiving flumazenil;


• confusion, fear, panic attack; or


• fast or uneven heart rate.

Less serious side effects include:

• pain or irritation where the medicine was injected;


• agitation or tremors (shaking);


• warmth, redness, or tingly feeling under your skin;


• dizziness;


• sweating or shivering;


• headache;


• blurred vision; or


• ringing in your ears.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about flumazenil (Romazicon)?

You should not receive this medication if you are allergic to flumazenil or any type of benzodiazepine sedative, or if you have taken an overdose of antidepressant medication such as Elavil, Janimine, Tofranil, Norpramin, Desyrel, Ascendin, Anafranil, Sinequan, Pamelor, Vivactil, or Surmontil.

Before receiving flumazenil, tell your doctor if you have a seizure disorder, liver disease, a history of head injury, uncontrolled muscle twitches, a breathing disorder, anxiety or panic disorder, or a history of drug or alcohol addiction.

You may have temporary amnesia while you are coming out of sedation after a surgery. You may not remember everything going on around you during this time.

Flumazenil can cause side effects that may impair your thinking or reactions. For at least 18 hours after you leave the hospital or surgery center, do not drive or do anything else that requires you to be awake and alert. Continue to limit these activities until you no longer feel sedated (weak, drowsy, or dizzy).

Even though you may feel alert after waking up from sedation, your judgment or reactions may still be impaired. Follow your caregivers' instructions about limiting activities after receiving flumazenil.

Do not drink alcohol for at least 18 hours after receiving flumazenil, or if you still feel sedated.

Related Drug Centers

• Romazicon

Elocon Lotion

DRUG DESCRIPTION

ELOCON (mometasone furoate topical solution) Lotion, 0.1%, contains mometasone
furoate, USP for dermatologic use. Mometasone furoate is a synthetic corticosteroid
with anti-inflammatory activity.

Chemically, mometasone furoate is 9α,21-dichloro-11β,17-dihydroxy-16α- methylpregna-1,4-diene-3,20-dione 17-(2-furoate), with the empirical formula C27H30Cl2O6, a molecular weight of 521.4 and the following structural formula:

Mometasone furoate is a white to off-white powder insoluble in water, freely soluble in acetone and in methylene chloride and sparingly soluble in heptane.

Each gram of ELOCON Lotion, 0.1%, contains: 1 mg mometasone furoate, USP in a lotion base of isopropyl alcohol (40%), propylene glycol, hydroxypropylcellulose, sodium phosphate monobasic monohydrate and water. May also contain phosphoric acid used to adjust the pH to approximately 4.5.

What are the possible side effects of mometasone topical (Elocon)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing mometasone topical through your skin, such as:

• blurred vision, or seeing halos around lights;


• mood changes;


• sleep problems (insomnia);


• weight gain, puffiness in your face; or

...

Read All Potential Side Effects and See Pictures of Elocon Lotion »

What are the precautions when taking mometasone furoate lotion (Elocon Lotion)?

Before using mometasone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: poor blood circulation, diabetes, immune system problems.

Corticosteroids can make skin infections worse and more difficult to treat. Tell your doctor if you have a skin infection so it can be treated. Tell your doctor promptly if your condition does not improve or if you have worsening skin symptoms.

Rarely, using corticosteroid medications for a long time or over large areas of skin can make it more difficult...

Read All Potential Precautions of Elocon Lotion »

Elocon Lotion Consumer (continued)

SIDE EFFECTS: Burning, itching, or stinging may occur when you apply this medication, but usually only lasts a short time. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if any of these unlikely but serious side effects occur: stretch marks, skin thinning/discoloration, acne, hair bumps (folliculitis).

Rarely, it is possible this medication will be absorbed from the skin into the bloodstream. This can lead to side effects of too much corticosteroid. These side effects are more likely in children, and in people who use this medication for a long time or over large areas of the skin. Tell your doctor right away if any of the following side effects occur: unusual/extreme tiredness, weight loss, headache, swelling ankles/feet, increased thirst/urination, vision problems.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using mometasone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: poor blood circulation, diabetes, immune system problems.

Corticosteroids can make skin infections worse and more difficult to treat. Tell your doctor if you have a skin infection so it can be treated. Tell your doctor promptly if your condition does not improve or if you have worsening skin symptoms.

Rarely, using corticosteroid medications for a long time or over large areas of skin can make it more difficult for your body to respond to physical stress. Therefore, before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used this medication within the past few months.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Though it is unlikely, this medication may slow down a child's growth if used for a long time. The effect on final adult height is unknown. See the doctor regularly so your child's height can be checked.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Elocon Lotion Patient Information Including Side Effects

Brand Names: Elocon

Generic Name: mometasone topical (Pronunciation: moe MET a sone)

• What is mometasone topical (Elocon Lotion)?


• What are the possible side effects of mometasone topical (Elocon Lotion)?


• What is the most important information I should know about mometasone topical (Elocon Lotion)?


• What should I discuss with my healthcare provider before using mometasone topical (Elocon Lotion)?


• How should I use mometasone topical (Elocon Lotion)?


• What happens if I miss a dose (Elocon Lotion)?


• What happens if I overdose (Elocon Lotion)?


• What should I avoid while using mometasone topical (Elocon Lotion)?


• What other drugs will affect mometasone topical (Elocon Lotion)?


• Where can I get more information?

What is mometasone topical (Elocon Lotion)?

Mometasone is a topical (for the skin) steroid. It reduces the actions of chemicals in the body that cause inflammation, redness, and swelling.

Mometasone topical is used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis.

Mometasone topical may also be used for other purposes not listed in this medication guide.

What are the possible side effects of mometasone topical (Elocon Lotion)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing mometasone topical through your skin, such as:

• blurred vision, or seeing halos around lights;


• mood changes;


• sleep problems (insomnia);


• weight gain, puffiness in your face; or


• muscle weakness, feeling tired.

Less serious side effects may include:

• mild skin rash, itching, burning, redness, or dryness;


• thinning or softening of your skin;


• skin rash or irritation around your mouth;


• swollen hair follicles;


• spider veins;


• numbness or tingling;


• changes in color of treated skin;


• blisters, pimples, or crusting of treated skin; or


• stretch marks.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about mometasone topical (Elocon Lotion)?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts or for longer than recommended. Topical steroid medicine can be absorbed through the skin, which may cause steroid side effects throughout the body.

Do not cover treated skin areas with a bandage or other covering unless your doctor has told you to. If you are treating the diaper area of a baby, do not use plastic pants or tight-fitting diapers. Covering the skin that is treated with mometasone topical can increase the amount of medicine your skin absorbs, which may lead to unwanted side effects. Follow your doctor's instructions.

Do not use this medication on a child without a doctor's advice. Children are more likely to absorb large amounts of a topical steroid through the skin. Steroid absorption in children may cause unwanted side effects, or a delay in growth with long-term use. Talk with your doctor if you think your child is not growing at a normal rate while using this medication over a long treatment period.

Contact your doctor if your condition does not improve within 2 weeks of using this medicine, or if you develop signs of a bacterial, fungal, or viral skin infection.

Related Drug Centers

• Elocon


• Elocon Lotion


• Elocon Ointment

Follistim AQ Cartridge

DRUG DESCRIPTION

Follistim AQ Cartridge contains human follicle-stimulating hormone (hFSH),
a glycoprotein hormone which is manufactured by recombinant DNA (rDNA) technology.
The active drug substance, follitropin beta, has a dimeric structure containing
two glycoprotein subunits (alpha and beta). Both the 92 amino acid alpha-chain
and the 111 amino acid beta-chain have complex heterogeneous structures arising
from two N-linked oligosaccharide chains. Follitropin beta is synthesized in
a Chinese hamster ovary (CHO) cell line that has been transfected with a plasmid
containing the two subunit DNA sequences encoding for hFSH. The purification
process results in a highly purified preparation with a consistent hFSH isoform
profile and high specific activity [as determined by the Ph. Eur. test for FSH
in vivo bioactivity and on the basis of the molar extinction coefficient at
277 nm ( εs:mg^-1cm^-1) = 1.066].

The biological activity is determined by measuring the increase in ovary weight
in female rats. The intrinsic luteinizing hormone (LH) activity in follitropin
beta is less than 1 international unit per 40,000 international units FSH. The
compound is considered to contain no LH activity.

The amino acid sequence and tertiary structure of the product are indistinguishable
from that of hFSH of urinary source. Also, based on available data derived from
physico-chemical tests and bioassay, follitropin beta and follitropin alfa,
another recombinant follicle-stimulating hormone product, are indistinguishable.

Follistim AQ Cartridge is a ready for use, prefilled with solution, disposable
cartridge containing either 175 IU of follitropin beta in 0.210 mL (833 IU/mL),
350 IU in 0.420 mL (833 IU/mL), 650 IU in 0.780 mL (833 IU/mL) or 975 IU in
1.170 mL (833 IU/mL) of aqueous solution for multiple dose use, with a maximal
deliverable dose of either 150 IU, 300 IU, 600 IU or 900 IU, respectively. Inactive
ingredients in the cartridges include: benzyl alcohol NF 10 mg/mL; L-methionine
USP 0.5 mg/mL; polysorbate 20 NF 0.2 mg/mL; sodium citrate (dihydrate) USP 14.7
mg/mL; sucrose NF 50 mg/mL; and water for injection USP. Hydrochloric acid NF
and/or sodium hydroxide NF are used to adjust the pH to 7.

Follistim AQ Cartridge is for use only with the Follistim Pen, which features
an adjustable dosing system for administering the drug in a microvolume of solution.
The Follistim Pen with Follistim AQ Cartridge is intended for SUBCUTANEOUS USE
ONLY. The recombinant protein in Follistim AQ Cartridge has been standardized
for FSH in vivo bioactivity in terms of the WHO International Standard for Follicle
Stimulating Hormone (FSH) Recombinant, Human for Bioassay (code 92/642), issued
by the World Health Organization Expert Committee on Biological Standardization
(1995). Under current storage conditions, Follistim AQ may contain up to 11%
of oxidized follitropin beta.

In clinical trials with Follistim, serum antibodies to FSH or anti-CHO cell
derived proteins were not detected in any of the treated patients after exposure
to Follistim for up to three cycles.

What are the possible side effects of follicle stimulating hormone (Follistim, Follistim AQ, Gonal-F, Gonal-f RFF, Gonal-f RFF Pen)?

Stop using follicle stimulating hormone and seek emergency medical attention or notify your doctor immediately if you experience any of the following serious side effects:

• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);


• pain, warmth, redness, numbness, or tingling in an arm or leg (which may indicate a blood clot);


• confusion, severe dizziness, severe headache; or

...

Read All Potential Side Effects and See Pictures of Follistim AQ Cartridge »

Follistim AQ Cartridge Patient Information Including Side Effects

Brand Names: Follistim, Follistim AQ, Gonal-F, Gonal-f RFF, Gonal-f RFF Pen

Generic Name: follicle stimulating hormone (injectable) (Pronunciation: PAH lich cull STIM u lay ting HORE moan)

• What is follicle stimulating hormone (Follistim AQ Cartridge)?


• What are the possible side effects of follicle stimulating hormone (Follistim AQ Cartridge)?


• What is the most important information I should know about follicle stimulating hormone (Follistim AQ Cartridge)?


• What should I discuss with my healthcare provider before using follicle stimulating hormone (Follistim AQ Cartridge)?


• How should I use follicle stimulating hormone (Follistim AQ Cartridge)?


• What happens if I miss a dose (Follistim AQ Cartridge)?


• What happens if I overdose (Follistim AQ Cartridge)?


• What should I avoid while using follicle stimulating hormone (Follistim AQ Cartridge)?


• What other drugs will affect follicle stimulating hormone (Follistim AQ Cartridge)?


• Where can I get more information?

What is follicle stimulating hormone (Follistim AQ Cartridge)?

Follicle stimulating hormone (FSH) is a naturally occurring hormone. FSH is important in the development of follicles (eggs) produced by the ovaries. FSH is also important in the development of sperm.

Follicle stimulating hormone is used to stimulate a follicle (egg) to develop and mature. It is used when a woman desires pregnancy and her ovaries can produce a follicle but hormonal stimulation is not sufficient to make the follicle mature. Follicle stimulating hormone is also used to stimulate the development of multiple eggs for in vitro fertilization. Follicle stimulating hormone can be used by men to increase the production of sperm.

Follicle stimulating hormone may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of follicle stimulating hormone (Follistim AQ Cartridge)?

Stop using follicle stimulating hormone and seek emergency medical attention or notify your doctor immediately if you experience any of the following serious side effects:

• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);


• pain, warmth, redness, numbness, or tingling in an arm or leg (which may indicate a blood clot);


• confusion, severe dizziness, severe headache; or


• difficulty breathing.

Approximately 5% of patients treated with follicle stimulating hormone develop ovarian hyperstimulation syndrome (OHSS), especially after the first cycle of therapy. Symptoms of OHSS include severe pelvic pain, swelling of the hands or legs, abdominal pain and swelling, shortness of breath, weight gain, low urine output, diarrhea, and nausea or vomiting. OHSS can be fatal. Notify your doctor immediately or seek emergency medical attention if you develop any of these symptoms.

Other side effects may also occur. Notify your doctor if you experience

• ovarian enlargement presenting as abdominal or pelvic pain, tenderness, pressure, or swelling;


• nausea, vomiting, diarrhea, or flatulence (gas);


• fever or chills;


• headache;


• dizziness;


• rapid pulse or heart rate;


• muscle or joint weakness or aching;


• breast tenderness;


• spotting or menstrual changes;


• pain, swelling, or irritation at the injection site; or


• dry skin, a rash, or hair loss.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about follicle stimulating hormone (Follistim AQ Cartridge)?

Treatment with follicle stimulating hormone increases the likelihood of multiple births. Multiple births carry additional risk both for the mother and for fetuses. Discuss the risk of multiple births with your healthcare provider.

Related Drug Centers

• Gonal-F


• Gonal-f RFF


• Follistim


• Follistim AQ Cartridge

Folvite

(Generic versions may still be available.)

DRUG DESCRIPTION

Folic Acid, N-(p(((2-Amino-4-hydroxy-6-pteridinyl)-methyl)Amino)benzoyl) glutamic acid, is a complex organic compound present in liver, yeast and other substances, and which may be prepared synthetically.

Tablets: 1 mg folic acid

Parenteral: Each ml of folic acid-solution contains sodium folate equivalent to 5 mg of folic acid.

Inactive ingredients: Sequestrene sodium 0.2% and water for injection qs 100%. Sodium hydroxide to approx. pH 9.

Preservative: Benzyl alcohol 1.5%.

What are the precautions when taking folic acid (Folvite)?

Before taking this product, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this product, tell your doctor or pharmacist your medical history, especially of: vitamin B-12 deficiency (pernicious anemia).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Folic acid is safe to take during pregnancy when used as directed. It is included in prenatal vitamin products. Certain spinal cord birth defects may be prevented by taking adequate amounts of folic acid during...

Read All Potential Precautions of Folvite »

Folvite Consumer (continued)

SIDE EFFECTS: Folic acid usually has very few side effects. If you have any unusual effects from taking this product, tell your doctor or pharmacist promptly.

If your doctor has directed you to use this product, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this product do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking this product, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this product, tell your doctor or pharmacist your medical history, especially of: vitamin B-12 deficiency (pernicious anemia).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Folic acid is safe to take during pregnancy when used as directed. It is included in prenatal vitamin products. Certain spinal cord birth defects may be prevented by taking adequate amounts of folic acid during pregnancy. Consult your doctor for more details.

Folic acid passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.

Flovent

DRUG DESCRIPTION

The active component of FLOVENT (fluticasone propionate) 44 mcg Inhalation Aerosol, FLOVENT (fluticasone propionate) 110 mcg Inhalation Aerosol, and FLOVENT 220 mcg Inhalation Aerosol is fluticasone propionate, a glucocorticoid having the chemical name S-(fluoromethyl)6a,9-difluoro-11b,17-dihydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17b-carbothioate, 17-propionate and the following chemical structure:

Fluticasone propionate is a white to off-white powder with a molecular weight of 500.6. It is practically insoluble in water, freely soluble in dimethyl sulfoxide and dimethylformamide, and slightly soluble in methanol and 95% ethanol.

FLOVENT (fluticasone propionate) 44 mcg Inhalation Aerosol, FLOVENT (fluticasone propionate) 110 mcg Inhalation Aerosol, and FLOVENT (fluticasone propionate) 220 mcg Inhalation Aerosol are pressurized, metered-dose aerosol units intended for oral inhalation only. Each unit contains a microcrystalline suspension of fluticasone propionate (micronized) in a mixture of 2 chlorofluorocarbon propellants (trichlorofluoromethane and dichlorodifluoromethane) with soya lecithin. Each actuation of the inhaler delivers 50, 125, or 250 mcg of fluticasone propionate from the valve and 44, 110, or 220 mcg, respectively, of fluticasone propionate from the actuator.

What are the possible side effects of fluticasone inhalation (Flovent Diskus, Flovent HFA)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• weakness, tired feeling, nausea, vomiting, feeling like you might pass out;


• skin rash, bruising, severe tingling, numbness, pain, muscle weakness;


• blurred vision, eye pain, or seeing halos around lights;


• signs of infection such as...

Read All Potential Side Effects and See Pictures of Flovent »

What are the precautions when taking fluticasone propionate (Flovent)?

Before using fluticasone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: current/past infections (such as tuberculosis, herpes), certain eye problems (cataracts, glaucoma, herpes infection of the eye), bone loss (osteoporosis), liver disease.

This medication may mask signs of infection. It can make you more likely to get infections or may worsen any current infections. Therefore, wash your hands well to prevent the spread of infection. Avoid contact with people who have infections that may...

Read All Potential Precautions of Flovent »

Flovent Consumer (continued)

SIDE EFFECTS: Hoarseness or throat irritation may occur. If either of these effects persists or worsens, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: white patches in your mouth/on your tongue, signs of infection (such as fever, chills, cough, persistent sore throat), vision problems, increased thirst/urination, easy bruising/bleeding, mental/mood changes (such as depression, mood swings, agitation), bone pain.

Infrequently, this medication may cause sudden severe wheezing/trouble breathing immediately after you use it. If this occurs, use your quick-relief inhaler and get medical help right away.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using fluticasone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: current/past infections (such as tuberculosis, herpes), certain eye problems (cataracts, glaucoma, herpes infection of the eye), bone loss (osteoporosis), liver disease.

This medication may mask signs of infection. It can make you more likely to get infections or may worsen any current infections. Therefore, wash your hands well to prevent the spread of infection. Avoid contact with people who have infections that may spread to others (such as chickenpox, measles, flu). Consult your doctor if you have been exposed to an infection or for more details.

If you have switched from a corticosteroid taken by mouth (such as prednisone tablets) to this inhaler within the past 12 months, or if you have been using this product in higher-than-usual doses for a long time, it may be more difficult for your body to respond to physical stress. Therefore, before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used a corticosteroid taken by mouth within the past 12 months. Tell your doctor right away if you develop unusual/extreme tiredness or weight loss. Carry a warning card or medical ID bracelet that says you use (or have used) corticosteroid medications.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

This medication may slow down a child's growth if used for a long time, but poorly controlled asthma can also slow down growth. The effect on final adult height is unknown. See the doctor regularly so your child's height can be checked.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Flovent Patient Information Including Side Effects

Brand Names: Flovent Diskus, Flovent HFA

Generic Name: fluticasone inhalation (Pronunciation: floo TIK a zone)

• What is fluticasone inhalation (Flovent)?


• What are the possible side effects of fluticasone inhalation (Flovent)?


• What is the most important information I should know about fluticasone inhalation (Flovent)?


• What should I discuss with my healthcare provider before using fluticasone inhalation (Flovent)?


• How should I use fluticasone inhalation (Flovent)?


• What happens if I miss a dose (Flovent)?


• What happens if I overdose (Flovent)?


• What should I avoid while using fluticasone inhalation (Flovent)?


• What other drugs will affect fluticasone inhalation (Flovent)?


• Where can I get more information?

What is fluticasone inhalation (Flovent)?

Fluticasone is a steroid. It prevents the release of substances in the body that cause inflammation.

Fluticasone inhalation is used to prevent asthma attacks. It will not treat an asthma attack that has already begun.

Fluticasone may also be used for other purposes not listed in this medication guide.

What are the possible side effects of fluticasone inhalation (Flovent)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• weakness, tired feeling, nausea, vomiting, feeling like you might pass out;


• skin rash, bruising, severe tingling, numbness, pain, muscle weakness;


• blurred vision, eye pain, or seeing halos around lights;


• signs of infection such as fever, chills, sore throat, ear pain, flu symptoms;


• wheezing or breathing problems after using this medication; or


• worsening asthma symptoms.

Less serious side effects may include:

• headache;


• dryness in your mouth, nose, or throat;


• white patches or sores inside your mouth or on your lips;


• stuffy nose, sinus pain, cough; or


• hoarseness or deepened voice.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about fluticasone inhalation (Flovent)?

Do not use fluticasone inhalation to treat an asthma attack that has already begun. It will not work fast enough to reverse your symptoms. Use another, faster-acting inhalation medication to treat an asthma attack.

Contact your doctor if your asthma symptoms do not improve after using fluticasone inhalation for 2 weeks.

Seek medical attention if you think any of your asthma medications are not working as well as usual. An increased need for medication could be an early sign of a serious asthma attack.

Your dosage needs may change if you have surgery, are ill, are under stress, or have recently had an asthma attack. Talk with your doctor if any of your asthma medications do not seem to work as well in treating or preventing asthma attacks.

If you were switched from an oral (taken by mouth) steroid to fluticasone inhalation, you may need to go back to taking the oral medicine if you are under stress or have an asthma attack or other medical emergency. Carry an identification card or wear a medical alert ID to let others know that you may need an oral steroid in an emergency.

Related Drug Centers

• Flovent


• Flovent HFA

Alupent

DRUG DESCRIPTION

Alupent (metaproterenol sulfate USP) Inhalation Aerosol is a bronchodilator
administered by oral inhalation. The Alupent Inhalation Aerosol containing 75
mg of metaproterenol sulfate as micronized powder is sufficient medication for
100 inhalations. The Alupent (metaproterenol sulfate) Inhalation Aerosol containing 150 mg of metaproterenol
sulfate as micronized powder is sufficient medication for 200 inhalations. Each
metered dose delivers through the mouthpiece 0.65 mg of metaproterenol sulfate
(each ml contains 15 mg). The inert ingredients are dichlorodifluoromethane,
dichlorotetrafluoroethane and trichloromonofluoromethane as propellants, and
sorbitan trioleate. Alupent (metaproterenol sulfate) , 1-(3,5-dihydroxyphenyl)-2-isopropylaminoethanol
sulfate, is a white, crystalline, racemic mixture of two optically active isomers.
It has the following chemical structure:

What are the possible side effects of metaproterenol (Alupent, Metaprel)?

If you experience any of the following serious side effects, stop taking metaproterenol and seek emergency medical attention or contact your doctor immediately:

• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or


• chest pains or an irregular heart beat.

Other, less serious side effects may be more likely to occur. Continue to take metaproterenol and talk to your doctor if you experience

• headache, dizziness,...

Read All Potential Side Effects and See Pictures of Alupent »

Alupent Patient Information Including Side Effects

Brand Names: Alupent, Metaprel

Generic Name: metaproterenol (Pronunciation: meh ta proe TER e nall)

• What is metaproterenol (Alupent)?


• What are the possible side effects of metaproterenol (Alupent)?


• What is the most important information I should know about metaproterenol (Alupent)?


• What should I discuss with my healthcare provider before taking metaproterenol (Alupent)?


• How should I take metaproterenol (Alupent)?


• What happens if I miss a dose (Alupent)?


• What happens if I overdose (Alupent)?


• What should I avoid while taking metaproterenol (Alupent)?


• What other drugs will affect metaproterenol (Alupent)?


• Where can I get more information?

What is metaproterenol (Alupent)?

Metaproterenol is a bronchodilator. It works by relaxing muscles in the airways to improve breathing.

Metaproterenol is used to treat conditions such as asthma, bronchitis, and emphysema.

Metaproterenol may also be used for conditions other than those listed in this medication guide.

What are the possible side effects of metaproterenol (Alupent)?

If you experience any of the following serious side effects, stop taking metaproterenol and seek emergency medical attention or contact your doctor immediately:

• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or


• chest pains or an irregular heart beat.

Other, less serious side effects may be more likely to occur. Continue to take metaproterenol and talk to your doctor if you experience

• headache, dizziness, lightheadedness, or insomnia;


• tremor or nervousness;


• sweating;


• nausea, vomiting, or diarrhea; or


• dry mouth.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about metaproterenol (Alupent)?

It is very important that you use the metaproterenol inhaler or nebulizer properly, so that the medicine gets into the lungs. Your doctor may want you to use a spacer with the inhaler. Talk to your doctor about proper inhaler and nebulizer use.

Seek medical attention if you notice that you require more than your usual or more than the maximum amount of any asthma medication in a 24-hour period. An increased need for medication could be an early sign of a serious asthma attack.

Related Drug Centers

• Alupent

Alphanate

DRUG DESCRIPTION

Antihemophilic Factor (Human), Alphanate (antihemophilic factor) ®, Solvent Detergent / Heat Treated, is a single dose, sterile, lyophilized concentrate of Factor VIII (AHF) intended for intravenous administration in the treatment of hemophilia A, or acquired Factor VIII deficiency.

Alphanate (antihemophilic factor) ® is prepared from pooled human plasma by cryoprecipitation of
the Factor VIII, fractional solubilization, and further purification employing
heparin-coupled, cross-linked agarose which has an affinity to the heparin binding
domain of vWf/FVIII:C complex.¹ The product is treated with a mixture
of tri(n-butyl) phosphate (TNBP) and polysorbate 80 to reduce the risks of transmission
of viral infection. In order to provide an additional safeguard against potential
non-lipid enveloped viral contaminants, the product is also subjected to a 80
°C heat treatment step for 72 hours. However, no procedure has been shown
to be totally effective in removing viral infectivity from coagulation factor
products.

Alphanate® is labeled with the antihemophilic factor potency (Factor VIIIC
activity) expressed in International Units (I U) per vial, which is referenced
to the WHO International Standard.

Alphanate (antihemophilic factor) ® contains Albumin (Human) as a stabilizer, resulting in a final container concentrate with a specific activity of at least 5 IU FVIII:C/mg total protein. Prior to the addition of the Albumin (Human) stabilizer, the specific activity is significantly higher.

When reconstituted with the appropriate volume of Sterile Water for Injection,
USP, Alphanate (antihemophilic factor) ® contains 0.3 - 0.9 g Albumin (Human)/100 mL; NMT 5 mmol
calcium/L; NMT 750 µg glycine/IU FVIIIC; NMT 1.0 U heparin/mL; 10 - 40
mmol histidine/L; NMT 0.1 mg imidazole/mL; 50 - 200 mmol arginine/L; NMT 1.0
µg polyethylene glycol and polysorbate 80/IU FVIII:C; NMT 10 mEq sodium/vial;
and NMT 0.1 µg TNBP/IU FVIIIC.

What are the possible side effects of antihemophilic factor (factor VIII)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);


• fever, chills, runny nose, and drowsiness followed about 2 weeks later by a rash and joint pain;


• fast heart rate, chest pain, trouble...

Read All Potential Side Effects and See Pictures of Alphanate »

What are the precautions when taking antihemophilic factor (Alphanate)?

Before using this medication, tell your doctor or pharmacist if you are allergic to any antihemophilic factor (factor VIII) products; or to animal proteins (e.g., mouse); or to natural rubber/latex (found in the packaging of some brands); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

Manufacturers of some brands of this medication recommend that you monitor your heartbeat during treatment. If your heart starts to beat faster, it is recommended that you give this medication more slowly or temporarily stop the infusion until your heart rate returns to normal....

Read All Potential Precautions of Alphanate »

What are the possible side effects of antihemophilic factor (factor VIII)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);


• fever, chills, runny nose, and drowsiness followed about 2 weeks later by a rash and joint pain;


• fast heart rate, chest pain, trouble...

Read All Potential Side Effects and See Pictures of Alphanate »

What are the precautions when taking antihemophilic factor (Alphanate)?

Before using this medication, tell your doctor or pharmacist if you are allergic to any antihemophilic factor (factor VIII) products; or to animal proteins (e.g., mouse); or to natural rubber/latex (found in the packaging of some brands); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

Manufacturers of some brands of this medication recommend that you monitor your heartbeat during treatment. If your heart starts to beat faster, it is recommended that you give this medication more slowly or temporarily stop the infusion until your heart rate returns to normal....

Read All Potential Precautions of Alphanate »

What are the possible side effects of antihemophilic factor (factor VIII)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);


• fever, chills, runny nose, and drowsiness followed about 2 weeks later by a rash and joint pain;


• fast heart rate, chest pain, trouble...

Read All Potential Side Effects and See Pictures of Alphanate »

What are the precautions when taking antihemophilic factor (Alphanate)?

Before using this medication, tell your doctor or pharmacist if you are allergic to any antihemophilic factor (factor VIII) products; or to animal proteins (e.g., mouse); or to natural rubber/latex (found in the packaging of some brands); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

Manufacturers of some brands of this medication recommend that you monitor your heartbeat during treatment. If your heart starts to beat faster, it is recommended that you give this medication more slowly or temporarily stop the infusion until your heart rate returns to normal....

Read All Potential Precautions of Alphanate »

Alphanate Consumer (continued)

SIDE EFFECTS: Flushing of the face, nausea, vomiting, and fast heartbeat may sometimes occur and can be lessened by giving this medication more slowly. Burning/redness/irritation at the injection site, fever, chills, and headache may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: signs of anemia (e.g., tiredness, low energy, pale skin color, shortness of breath), new or worsening bleeding/bruising.

This medication is made from human blood. There is a very small chance that you may get infections from this medication (e.g., viral infections such as hepatitis), even though careful screening of blood donors, special manufacturing processes, and many tests are all used to reduce this risk. Discuss the benefits and risks of treatment with your doctor. Tell your doctor immediately if you develop any signs of hepatitis or other infection, including fever, persistent sore throat, unusual tiredness, unusual drowsiness, joint pain, persistent nausea/vomiting, stomach/abdominal pain, yellowing eyes/skin, dark urine.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, chest discomfort/tightness.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using this medication, tell your doctor or pharmacist if you are allergic to any antihemophilic factor (factor VIII) products; or to animal proteins (e.g., mouse); or to natural rubber/latex (found in the packaging of some brands); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

Manufacturers of some brands of this medication recommend that you monitor your heartbeat during treatment. If your heart starts to beat faster, it is recommended that you give this medication more slowly or temporarily stop the infusion until your heart rate returns to normal. Consult your doctor for more details.

Since this medication is made from human blood, there is a very small chance that you may get infections from it (e.g., viral infections such as hepatitis). It is recommended that you get the appropriate vaccinations (e.g., for hepatitis A and B) and that people giving this medication handle the medication with special caution to prevent virus infections. Consult your doctor for more details.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

Alphanate Patient Information Including Side Effects

Brand Names: Advate rAHF-PFM, Alphanate, Helixate, Helixate FS, Hemofil-M, Humate-P, Koate-DVI, Koate-HP, Kogenate, Kogenate FS, Monarc-M, Monoclate-P, Recombinate, Refacto

Generic Name: antihemophilic factor (factor VIII) (injection) (Pronunciation: an TEE hee moe FIH lick FAC tor)

• What is antihemophilic factor (factor VIII) (Alphanate)?


• What are the possible side effects of antihemophilic factor (factor VIII)?


• What is the most important information I should know about antihemophilic factor (factor VIII)?


• What should I discuss with my healthcare provider before using antihemophilic factor (factor VIII)?


• How should I use antihemophilic factor (factor VIII)?


• What happens if I miss a dose?


• What happens if I overdose?


• What should I avoid while using antihemophilic factor (factor VIII)?


• What other drugs will affect antihemophilic factor (factor VIII)?


• Where can I get more information?

What is antihemophilic factor (factor VIII) (Alphanate)?

Antihemophilic factor (factor VIII) is a naturally occurring protein in the blood that helps blood to clot. A lack of factor VIII is the cause of hemophilia A.

Antihemophilic factor (factor VIII) is used to treat or prevent bleeding in people with hemophilia A.

Antihemophilic factor (factor VIII) may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of antihemophilic factor (factor VIII)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);


• fever, chills, runny nose, and drowsiness followed about 2 weeks later by a rash and joint pain;


• fast heart rate, chest pain, trouble breathing;


• feeling light-headed, fainting; or


• pain, redness, swelling, or oozing where the medicine was injected.

Other, less serious side effects may be more likely to occur, such as:

• unusual taste in your mouth;


• cough, runny or stuffy nose;


• mild itching;


• swelling in your hands, ankles, or feet;


• headache or dizziness;


• mild nausea, diarrhea, stomach pain;


• sweating;


• joint pain; or


• chills or flushing (warmth or tingly feeling).

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What is the most important information I should know about antihemophilic factor (factor VIII)?

Some forms of this medication are made from human plasma (part of the blood) and may contain viruses and other infectious agents that can cause disease. Although donated human plasma is screened, tested, and treated to reduce the risk of it containing anything that could cause disease, there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.

Some viruses, such as parovovirus B19 and hepatitis A, may be more difficult to identify or remove from antihemophilic factor (factor VIII). Parovovirus can seriously affect pregnant women and people with weak immune systems. Symptoms of parovovirus B19 infection include fever, chills, runny nose, and drowsiness followed about 2 weeks later by a rash and joint pain. Symptoms of hepatitis A may include several days to weeks of poor appetite, tiredness, and low-grade fever followed by nausea, vomiting, and stomach pain. Dark-colored urine and jaundice (yellowing of the skin or eyes) may also occur. Contact your doctor if you develop any of these symptoms after treatment with antihemophilic factor (factor VIII).

Carry an ID card or wear a medical alert bracelet stating that you have hemophilia, in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you have a bleeding disorder.

Your body may develop antibodies to this medication, making it less effective. Contact your doctor if this medicine does not seem to be working as well as before in controlling your bleeding.

If you need to have any type of surgery, tell the surgeon ahead of time that you are using antihemophilic factor (factor VIII). You may need to stop using the medicine for a short time.

Related Drug Centers

• Alphanate

Fastin

(Generic versions may still be available.)

DRUG DESCRIPTION

Each phentermine hydrochloride capsule contains phentermine hydrochloride, 30 mg (equivalent to 24 mg Phentermine).

Phentermine Hydrochloride is a white crystalline powder, very soluble in water and alcohol. Chemically, the product is phenyl-tertiary-butylamine hydrochloride. Inactive Ingredients: F D & C Blue 1, Methylcellulose, Polyethylene Glycol, Starch, Titanium Dioxide, Sucrose and Invert Sugar. The branding ink used on the gelatin capsules contains: Ethyl Alcohol, F D & C Blue 1 Aluminum Lake, Isopropyl Alcohol, n-Butyl Alcohol, Propylene Glycol, Pharmaceutical Shellac (modified) or Refined Shellac (Food Grade).

What are the precautions when taking phentermine (Fastin)?

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to any other sympathomimetic amines (e.g., decongestants such as pseudoephedrine, stimulants such as amphetamine, appetite suppressants such as diethylpropion); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: uncontrolled high blood pressure, glaucoma, history of alcohol/drug abuse, vascular heart disease (e.g., chest pain, heart attack), mental/mood problems (e.g., severe anxiety, bipolar disorder, psychosis,...

Read All Potential Precautions of Fastin »

Fastin Consumer (continued)

SIDE EFFECTS: Dizziness, dry mouth, difficulty sleeping, irritability, nausea, vomiting, diarrhea, or constipation may occur. If these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: fast/irregular/pounding heartbeat, mental/mood changes (e.g., agitation, uncontrolled anger, hallucinations, nervousness), uncontrolled muscle movements, change in sexual ability/interest.

Stop taking this medication and seek immediate medical attention if any of these rare but very serious side effects occur: severe headache, slurred speech, seizure, weakness on one side of the body, vision changes (e.g., blurred vision).

This drug may infrequently cause serious (sometimes fatal) lung or heart problems (pulmonary hypertension, heart valve problems). The risk increases with longer use of this medication and use of this drug along with other appetite-suppressant drugs/herbal products. If you notice any of the following unlikely but very serious side effects, stop taking this medication and consult your doctor or pharmacist immediately: chest pain, difficulty breathing with exercise, decreased ability to exercise, fainting, swelling of the legs/ankles/feet.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to any other sympathomimetic amines (e.g., decongestants such as pseudoephedrine, stimulants such as amphetamine, appetite suppressants such as diethylpropion); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: uncontrolled high blood pressure, glaucoma, history of alcohol/drug abuse, vascular heart disease (e.g., chest pain, heart attack), mental/mood problems (e.g., severe anxiety, bipolar disorder, psychosis, schizophrenia), high blood pressure in the lungs (pulmonary hypertension), stroke, overactive thyroid (hyperthyroidism).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: diabetes, controlled high blood pressure, other heart problems (e.g., heart murmur, fast/irregular heartbeat, heart valve problems), kidney disease, seizure problem.

This drug may make you dizzy or (rarely) drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Avoid alcoholic beverages.

Before having surgery, tell your doctor or dentist that you are using this medication.

Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, elderly people may be at greater risk for dizziness and high blood pressure while using this drug.

During pregnancy, this medication should be used only when clearly needed. It is not recommended for use for long periods or in high doses near the expected delivery date because of possible harm to the unborn baby. Discuss the risks and benefits with your doctor. Infants born to mothers who have been using this medication for a long time or in high doses may have withdrawal symptoms such as irritability or extreme tiredness. Tell your doctor immediately if you notice any of these symptoms in your newborn.

This drug may pass into breast milk and could have undesirable effects on a nursing infant. Therefore, breast-feeding is not recommended while using this drug. Consult your doctor before breast-feeding.

Dimetane

(Generic versions may still be available.)

DRUG DESCRIPTION

The product is a bluish pink to pink syrup with a raspberry flavor. Each 5 mL (1 teaspoonful) contains:

Brompheniramine Maleate, USP ........................................2 mg




Phenylpropanolamine Hydrochloride, USP .........................12.5 mg




*Codeine Phosphate, USP .................................................10 mg




*(WARNING: May be habit forming)




Alcohol ..................................................................... 1.2%




In a palatable aromatic vehicle




Brompheniramine Maleate, USP: 2-Pyridinepropanamine,r-(4-bromophenyl)N, N-dimethyl-,(Z)-butenedioate(l:l).




Phenylpropanolamine Hydrochloride, USP: Benzenemethanol, a-(1-aminoethyl)-hydrochloride, (R*,S*)-( + ).




Codeine Phosphate, USP: Morphinan-6-01, 7,8,-didehydro-4,5-epoxy-3-methoxy-17- methyl-&,6a)-,phosphate (1:l) (salt), hemihydrate.




Antihistamine/Nasal Decongestan/Antitussive syrup for oral administratton.

INACTIVE INGREDIENTS: Citric Acid, USP; FD&C Blue No. 1; FD&C Red No. 40; Flavor; Glycerin, USP; Menthol, USP; Methylparaben, NF; Propylene Glycol, USP; Purified Water, USP; Sodium Benzoate, NF; Sodium Citrate, USP and Sorbitol Solution, USP.

What are the possible side effects of brompheniramine?

Stop taking brompheniramine and seek emergency medical attention if you experience a rare but serious allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take brompheniramine and talk to your doctor if you experience

• sleepiness, fatigue, or dizziness;


• headache;


• dry mouth; or


• difficulty urinating or an enlarged prostate.

Side effects other than...

Read All Potential Side Effects and See Pictures of Dimetane »

Dimetane Patient Information Including Side Effects

Brand Names: BroveX, BroveX CT, Dimetane, Dimetane Extentab, Dimetapp Allergy, Dimetapp Allergy Liquigel, Lodrane 12 Hour

Generic Name: brompheniramine (Pronunciation: brome feh NEER a meen)

• What is brompheniramine (Dimetane)?


• What are the possible side effects of brompheniramine?


• What is the most important information I should know about brompheniramine?


• What should I discuss with my healthcare provider before taking brompheniramine?


• How should I take brompheniramine?


• What happens if I miss a dose?


• What happens if I overdose?


• What should I avoid while taking brompheniramine?


• What other drugs will affect brompheniramine?


• Where can I get more information?

What is brompheniramine (Dimetane)?

Brompheniramine is an antihistamine. Brompheniramine blocks the effects of the naturally occurring chemical histamine in the body.

Brompheniramine is used to sneezing; runny nose; itching, watery eyes; hives; rashes; itching; and other symptoms of allergies and the common cold.

Brompheniramine may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of brompheniramine?

Stop taking brompheniramine and seek emergency medical attention if you experience a rare but serious allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take brompheniramine and talk to your doctor if you experience

• sleepiness, fatigue, or dizziness;


• headache;


• dry mouth; or


• difficulty urinating or an enlarged prostate.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about brompheniramine?

Use caution when driving, operating machinery, or performing other hazardous activities. Brompheniramine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking brompheniramine.

Do not crush, chew, or break the extended- or timed-release forms of brompheniramine. Swallow them whole. They are specially formulated to release the medication slowly in the body.

Related Drug Centers

• Dimetane

Nutropin AQ

DRUG DESCRIPTION

Nutropin AQ® [somatropin (rDNA origin) injection] is a human growth hormone
(hGH) produced by recombinant DNA technology. Nutropin AQ (somatropin rdna origin) has 191 amino acid
residues and a molecular weight of 22,125 daltons. The amino acid sequence of
the product is identical to that of pituitary-derived human growth hormone.
The protein is synthesized by a specific laboratory strain of E. coli
as a precursor consisting of the rhGH molecule preceded by the secretion signal
from an E. coli protein. This precursor is directed to the plasma membrane
of the cell. The signal sequence is removed and the native protein is secreted
into the periplasm so that the protein is folded appropriately as it is synthesized.

Nutropin AQ (somatropin rdna origin) is a highly purified preparation. Biological potency is determined using a cell proliferation bioassay. Nutropin AQ (somatropin rdna origin) may contain not more than fifteen percent deamidated growth hormone (GH) at expiration. The deamidated form of GH has been extensively characterized and has been shown to be safe and fully active.

Nutropin AQ (somatropin rdna origin) is a sterile liquid intended for subcutaneous administration. The product is nearly isotonic at a concentration of 5 mg of GH per mL and has a pH of approximately 6.0.

The Nutropin AQ (somatropin rdna origin) 2 mL vial contains 10 mg (approximately 30 International Units [IU]) somatropin, formulated in 17.4 mg sodium chloride, 5 mg phenol, 4 mg polysorbate 20, and 10 mM sodium citrate.

The 10 mg Nutropin AQ (somatropin rdna origin) 2 mL pen cartridge contains 10 mg (approximately 30 International Units) somatropin, formulated in 17.4 mg sodium chloride, 5 mg phenol, 4 mg polysorbate 20, and 10 mM sodium citrate.

The 20 mg Nutropin AQ (somatropin rdna origin) 2 mL pen cartridge contains 20 mg (approximately 60 International Units) somatropin, formulated in 17.4 mg sodium chloride, 5 mg phenol, 4 mg polysorbate 20, and 10 mM sodium citrate.

The Nutropin AQ (somatropin rdna origin) NuSpin 5 contains 5 mg (approximately 15 International Units) somatropin, formulated in 17.4 mg sodium chloride, 5 mg phenol, 4 mg polysorbate 20, and 10 mM sodium citrate.

The Nutropin AQ (somatropin rdna origin) NuSpin 10 contains 10 mg (approximately 30 International Units) somatropin, formulated in 17.4 mg sodium chloride, 5 mg phenol, 4 mg polysorbate 20, and 10 mM sodium citrate.

The Nutropin AQ (somatropin rdna origin) NuSpin 20 contains 20 mg (approximately 60 International Units) somatropin, formulated in 17.4 mg sodium chloride, 5 mg phenol, 4 mg polysorbate 20, and 10 mM sodium citrate.

What are the possible side effects of somatropin?

If you have Prader-Willi syndrome, call your doctor promptly if you develop signs of lung or breathing problems such as shortness of breath, coughing, or new or increased snoring. Rare cases of serious breathing problems have occurred in patients with Prader-Willi syndrome who use somatropin.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• sudden...

Read All Potential Side Effects and See Pictures of Nutropin AQ »

What are the precautions when taking somatropin (rdna origin) (Nutropin AQ)?

Before using somatropin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as benzyl alcohol found in some brands), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: eye problems (e.g., diabetic retinopathy), major surgery or trauma, severe breathing problems (acute respiratory failure), undergoing therapy for tumors (cancer), Prader-Willi syndrome (see Side Effects section above), normal growth has stopped (closed epiphyses).

Before using this medication, tell your doctor or pharmacist...

Read All Potential Precautions of Nutropin AQ »

Nutropin AQ Consumer (continued)

SIDE EFFECTS: Headache, nausea, vomiting, fatigue, muscle pain, or weakness may occur. If these symptoms continue or become bothersome, inform your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: development of a limp, persistent fatigue, unusual/unexplained weight gain, persistent cold intolerance, persistent slow heartbeat, fast heartbeat, ear pain/itching, hearing problems, joint/hip/knee pain, numbness/tingling, unusual increase in thirst or urination, swelling hands/ankles/feet, change in the appearance or size of any mole, severe headache, persistent nausea/vomiting, severe stomach/abdominal pain, vision problems or changes, seizure.

Rare (possibly fatal) lung/breathing problems may be caused by this medication in children with Prader-Willi syndrome. Those at higher risk include males, severely overweight children, or those with serious lung/breathing problems ( e.g., sleep apnea, lung infections, lung disease). Children should be checked for certain breathing problems (upper airway obstruction) before and during treatment. Heavy snoring or irregular breathing during sleep (sleep apnea) are signs of airway obstruction. Tell the doctor immediately if these signs occur. Also report any signs of lung infection, such as fever, persistent cough, or trouble breathing.

A serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Symptoms of a serious allergic reaction include: rash, itching/severe swelling (especially of the face/tongue/throat), dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using somatropin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients (such as benzyl alcohol found in some brands), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: eye problems (e.g., diabetic retinopathy), major surgery or trauma, severe breathing problems (acute respiratory failure), undergoing therapy for tumors (cancer), Prader-Willi syndrome (see Side Effects section above), normal growth has stopped (closed epiphyses).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: adrenal gland problems, diabetes or family history of diabetes, obesity, kidney disease, tumors (cancer), thyroid problems, back problems (scoliosis), a certain genetic condition (Turner syndrome).

When this medication is given to newborns, mix with sterile water for injection that does not contain a preservative. A preservative (benzyl alcohol) which may be found in the liquid used to mix this product can infrequently cause serious problems (sometimes death), if given by injection to an infant during the first months of life. The risk is greater with lower birth weight infants and is greater with increased amounts of benzyl alcohol. Symptoms include sudden gasping, low blood pressure, or a very slow heartbeat. Report these symptoms to the doctor immediately should they occur.

Caution is advised when using in the elderly because elderly patients may be more sensitive to its effects.

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

It is not known if this drug passes into breast milk. Consult your doctor before breast-feeding.

Nutropin AQ Patient Information Including Side Effects

Brand Names: Genotropin, Genotropin Miniquick, Humatrope, Norditropin, Norditropin Cartridge, Norditropin Nordiflex Pen, Nutropin, Nutropin AQ, Omnitrope, Saizen, Serostim, Tev-tropin, Zorbtive

Generic Name: somatropin (Pronunciation: soe ma TROE pin)

• What is somatropin (Nutropin AQ)?


• What are the possible side effects of somatropin?


• What is the most important information I should know about somatropin?


• What should I discuss with my healthcare provider before using somatropin?


• How should I use somatropin?


• What happens if I miss a dose?


• What happens if I overdose?


• What should I avoid while using somatropin?


• What other drugs will affect somatropin?


• Where can I get more information?

What is somatropin (Nutropin AQ)?

Somatropin is a form of human growth hormone. Human growth hormone is important in the body for the growth of bones and muscles.

Somatropin is used to treat growth failure in children and adults who lack natural growth hormone, and in those with chronic kidney failure, Noonan syndrome, Turner syndrome, short stature at birth with no catch-up growth, and other causes. Somatropin is also used to prevent severe weight loss in people with AIDS, or to treat short bowel syndrome.

Somatropin may also be used for other purposes not listed in this medication guide.

What are the possible side effects of somatropin?

If you have Prader-Willi syndrome, call your doctor promptly if you develop signs of lung or breathing problems such as shortness of breath, coughing, or new or increased snoring. Rare cases of serious breathing problems have occurred in patients with Prader-Willi syndrome who use somatropin.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• sudden and severe pain or tenderness in your upper stomach;


• nausea, vomiting, sweating, fever, fast heartbeat, yellowing of the skin or eyes;


• increased thirst and urination;


• sudden and severe pain behind your eyes, vision changes;


• swelling in your head, face, hands, or feet; or


• numbness or tingling in your wrist, hand, or fingers.

Less serious side effects may include:

• headache;


• redness, soreness, swelling, skin rash, itching, pain, or bruising where the medicine was injected;


• breast swelling;


• joint pain, swelling, or stiffness; or


• mild nausea, stomach pain, gas.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about somatropin?

Before you receive somatropin, tell your doctor about all your past and present medical conditions, especially allergies, trauma, surgery, diabetes, cancer, breathing problems, liver or kidney disease, scoliosis, high blood pressure, pancreas disorder, underactive thyroid, or a brain tumor.

Also tell your doctor about all other medications you use, especially steroids or diabetes medications. Your dosages of these medicines may need to be changed when you start using somatropin. Do not stop using a steroid suddenly or change any of your medication doses without your doctor's advice.

If you have Prader-Willi syndrome and are using somatropin, call your doctor promptly if you develop signs of lung or breathing problems such as shortness of breath, coughing, or new or increased snoring.

Call your doctor at once if you have sudden and severe pain or tenderness in your upper stomach, with nausea, vomiting, sweating, fever, fast heartbeat, and yellowing of the skin or eyes. You should also call your doctor promptly if you have vision changes and sudden, severe pain behind your eyes.

Related Drug Centers

• Omnitrope


• Genotropin


• Humatrope


• Tev-Tropin


• Norditropin


• Nutropin AQ


• Serostim


• Nutropin